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CASE REPORT
Year : 2020  |  Volume : 32  |  Issue : 2  |  Page : 203-206

The effect of topical bromfenac on intraretinal and subretinal fluid in neovascular age-related macular degeneration


1 Ophthalmology Unit, Neurosciences, Mental Health and Sensory Organs Department, St. Andrea Hospital, Sapienza University of Rome, Rome, Italy
2 Ophthalmology Unit, Department of Sense Organs, Sapienza University of Rome, Rome, Italy

Correspondence Address:
Solmaz Abdolrahimzadeh
Ophthalmology Unit, Neurosciences, Mental Health and Sensory Organs Department, St. Andrea Hospital, Sapienza University of Rome, Via Di Grottarossa 1035-1039, Rome 00189
Italy
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JOCO.JOCO_105_20

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Purpose: To report the effect of topical bromfenac, a non-steroidal anti-inflammatory drug (NSAID), in a case of neovascular age-related macular degeneration (AMD). Methods: An 85-year-old woman presented with a complaint of visual acuity reduction in the right eye. Comprehensive ophthalmological examination and retinal imaging were performed. Results: Best corrected visual acuity was 2/100. Fundus examination showed reticular pseudodrusen and a small hemorrhage in the fovea. Fluorescein angiography showed an active neovascular membrane. Spectral-domain optical coherence tomography (SD-OCT) confirmed diagnosis and revealed subretinal and intraretinal fluid. The patient refused recommended intravitreal anti-vascular endothelial growth factor treatment and received topical bromfenac 0.09% twice daily. Follow-up with SD-OCT showed subretinal followed by intraretinal fluid reduction at 16 weeks after treatment. Conclusion: Short-term reduction of subretinal and intraretinal fluid was observed with topical bromfenac monotherapy in neovascular AMD.


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